Dowcide 2

Dowcide 2 - Names and Identifiers

Name	2,4,5-Trichlorophenol
Synonyms	Nurelle Dowcide 2 2,4,5-TCP 202-467-8 NCI-C61187 QR BG DG EG Preventol I 2,4,5-Trichlorophenol 2,4,5-trichloro-pheno 2,4,5-TRICHLOROPHENOL phenol, 2,4,5-trichloro- epapesticidechemicalcode064210 2,4,5-trichlorophenolsaltof2,6-bis((dimethylamino)methyl)cyclohexanone
CAS	95-95-4
EINECS	202-467-8
InChI	InChI=1/C6H3Cl3O/c7-3-1-5(9)6(10)2-4(3)8/h1-2,10H

Dowcide 2 - Physico-chemical Properties

Molecular Formula	C6H3Cl3O
Molar Mass	197.45
Density	1,678 g/cm3
Melting Point	64-67 °C67-69 °C (lit.)
Boling Point	248 °C/740 mmHg (lit.)
Flash Point	253°C
Water Solubility	947.8mg/L(25 ºC)
Solubility	Soluble in ethanol and ligroin (U.S. EPA, 1985)
Vapor Presure	3.5 at 8 °C, 22 at 25 °C (quoted, Leuenberger et al., 1985a)
Appearance	Powder
Color	Colorless needles or gray flakes from pet ether
Odor	strong phenolic odor
Merck	14,9643
BRN	607569
pKa	pK1:7.37 (25°C)
Storage Condition	2-8°C
Stability	Stable. Note that this material creates dioxin in alkaline media at elevated temperatures.
Refractive Index	1.5300 (estimate)
Physical and Chemical Properties	Needle-like crystals with a phenolic taste. Melting point 68 ℃, boiling point 253 ℃, relative density 1.678(25 ℃). Flammable. Soluble in ethanol, ether, acetone, benzene, carbon tetrachloride, petroleum ether and other organic solvents, almost insoluble in water. Can sublimate, with weak alkaline and strong phenolic smell.

Dowcide 2 - Risk and Safety

Risk Codes	R22 - Harmful if swallowed R36/38 - Irritating to eyes and skin. R50/53 - Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. R52/53 - Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment. R39/23/24/25 - R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed. R11 - Highly Flammable R51/53 - Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S28 - After contact with skin, wash immediately with plenty of soap-suds. S60 - This material and its container must be disposed of as hazardous waste. S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. S28A - S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S36/37 - Wear suitable protective clothing and gloves. S16 - Keep away from sources of ignition.
UN IDs	UN 3077 9/PG 3
WGK Germany	3
RTECS	SN1400000
TSCA	Yes
HS Code	29081990
Hazard Class	6.1
Packing Group	III
Toxicity	Acute oral LD50 for guinea pigs 1,000 mg/kg, mice 600 mg/kg, rats 820 mg/kg (quoted, RTECS, 1985).

Dowcide 2 - Nature

Open Data Verified Data

needle-like crystals with phenolic flavor. Melting point 68. Boiling point 253 °c. The relative density is 1. 678(25 ℃). Flammable. Almost insoluble in water, soluble in ethanol, ether, acetone, carbon tetrachloride, petroleum ether, benzene and other organic solvents.

Last Update：2024-01-02 23:10:35

Dowcide 2 - Preparation Method

Open Data Verified Data

tetrachlorobenzene method this is 2,4,5-the traditional process of chlorophenol production, using tetrachlorobenzene as raw material by hydrolysis.

Last Update：2022-01-01 10:41:47

Dowcide 2 - Use

Open Data Verified Data

can be used for the preparation of a variety of herbicides, insecticides, fungicides; As antibacterial and antiseptic, widely used in the preparation of adhesives, rubber products and anti-corrosion emulsion of textile industry. It itself can be used as a disinfectant, its sodium salt is also a fungicide and preservative, used in manufacturing and leather industry; In medicine for the synthesis of chlorpropargyl iodine, sterilization of phenol and so on.

Last Update：2022-01-01 10:41:47

Dowcide 2 - Safety

Open Data Verified Data

ingestion by mistake or inhalation has high toxicity and strong irritation. Can be absorbed through the skin poisoning. Rat oral LD50 820mg/kg, guinea pig oral ld5oloooomg/kg.
glass bottles are lined with mats or iron barrels. Store in a cool and ventilated warehouse; Carry light and remove light during handling to prevent damage to the container.

Last Update：2022-01-01 10:41:48

Dowcide 2 - Reference Information

Henry's Law Constant	1.76 at 25 °C (estimated, Leuenberger et al., 1985a)
NIST chemical information	information provided by: webbook.nist.gov (external link)
EPA chemical substance information	information provided by: ofmpeb.epa.gov (external link)
uses	can be used to prepare a variety of herbicides, pesticides, fungicides; As antibacterial and antiseptic, widely used in the preparation of adhesives, anti-corrosion emulsion for rubber products and textile industry. It itself can be used as a disinfectant, its sodium salt is also a fungicide and preservative, used in manufacturing and leather industry; In medicine for the synthesis of chlorpropargyl iodine, sterilization of phenol and so on. used as a fungicide, gas chromatography comparative sample.
production method	put 2,3,5, 6-tetrachlorobenzene, Solid alkali and methanol into an autoclave, the temperature was controlled at 135-152 °c and the pressure at 0.5-1.4MPa for 14H. The reaction solution was cooled to 60 ° C., and methanol was recovered by distillation, and the residue was discharged. The crystals were cooled and filtered. The crystals were dissolved in water, heated to 70 ° C., added with sodium hydrosulfite, adjusted to pH = 9.2-9.6, added with activated carbon, and decolorized at 95 ° C. For half an hour. After filtering, the filtrate was cooled to below 15 °c, hydrochloric acid was added to pH = 2-3, and 2,4, 5-trichlorophenol was filtered and dried at 45 °c to obtain a finished product.
category	pesticide
toxicity grade	poisoning
Acute toxicity	oral-rat LD50: 820 mg/kg; Oral-mouse LD50: 600 mg/kg
explosive hazard characteristics	Thermal decomposition explosive
flammability hazard characteristics	flammability; Toxic chloride fumes from combustion
storage and transportation characteristics	The warehouse is ventilated and dried at low temperature, separate storage of food additives
extinguishing agent	water mist, foam, carbon dioxide, sand.
Occupational Standard	TWA 0.5 mg/m3
toxic substance data	information provided by: pubchem.ncbi.nlm.nih.gov (external link)